ENSDARG00000052518


Danio rerio

Features
Gene ID: ENSDARG00000052518
  
Biological name :stx4
  
Synonyms : stx4 / syntaxin 4
  
Possible biological names infered from orthology : P70452 / Q12846 / Stx4a
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 20627164
Gene end: 20642019
  
Corresponding Affymetrix probe sets: Dr.2778.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000068873
Ensembl peptide - ENSDARP00000154837
NCBI entrez gene - 323735     See in Manteia.
RefSeq - NM_200221
RefSeq Peptide - NP_956515
swissprot - Q7ZV18
ZFIN ID - ZDB-GENE-030131-2455
Ensembl - ENSDARG00000052518
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 STX4ENSG00000103496Homo sapiens
 Stx4aENSMUSG00000030805Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
stx1b / syntaxin 1B / P61264* / P61266*ENSDARG0000000050343
stx1a / syntaxin 1A (brain) / O35526* / Q16623* / syntaxin 1A*ENSDARG0000005899439
stx3a / syntaxin 3A / STX3* / Q64704* / Q13277* / syntaxin 3*ENSDARG0000000188037
stx2b / syntaxin 2b / STX2* / P32856* / syntaxin 2*ENSDARG0000006821735
STX3 / zgc:165520 / Q13277* / Q64704* / syntaxin 3*ENSDARG0000005198134
stx11a / syntaxin 11a / STX11* / O75558* / syntaxin 11*ENSDARG0000004403930
stx11b.2 / syntaxin 11b, tandem duplicate 2 / STX11* / O75558* / syntaxin 11*ENSDARG0000004223126
stx2a / syntaxin 2a / STX2* / P32856* / syntaxin 2*ENSDARG0000000461825
stx11b.1 / syntaxin 11b, tandem duplicate 1 / STX11* / O75558* / syntaxin 11*ENSDARG0000002929025


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR006011  Syntaxin, N-terminal domain
 IPR006012  Syntaxin/epimorphin, conserved site
 IPR010989  SNARE


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0031629 synaptic vesicle fusion to presynaptic active zone membrane IBA
 biological_processGO:0048278 vesicle docking IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008021 synaptic vesicle IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0031201 SNARE complex IBA
 molecular_functionGO:0000149 SNARE binding IBA
 molecular_functionGO:0005484 SNAP receptor activity IBA


Pathways (from Reactome)
Pathway description
Disinhibition of SNARE formation
ER-Phagosome pathway
Clathrin derived vesicle budding
Other interleukin signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000008723 prkcba / protein kinase C, beta a / PRKCB* / P68404* / P05771* / protein kinase C beta*  / reaction
 ENSDARG00000030775 sybl1 / synaptobrevin-like 1 / VAMP7* / P51809* / vesicle associated membrane protein 7*  / reaction / complex
 ENSDARG00000022254 prkcbb / Q7SY24 / protein kinase C, beta b / PRKCB* / P05771* / protein kinase C beta*  / reaction
 ENSDARG00000024116 vamp8 / vesicle-associated membrane protein 8 (endobrevin) / Q9BV40* / vesicle associated membrane protein 8*  / reaction / complex
 ENSDARG00000077037 txlna / taxilin alpha / P40222* / Q6PAM1*  / reaction / complex
 ENSDARG00000099841 PRKCA / si:ch73-374l24.1 / si:ch1073-370j18.1 / P17252* / protein kinase C alpha*  / reaction
 ENSDARG00000100435 Q7SXP0 / sec22bb / SEC22 homolog B, vesicle trafficking protein b / SEC22B* / O08547* / O75396* / Vesicle-trafficking protein SEC22b * / SEC22 homolog B, vesicle trafficking protein (gene/p...  / complex






 

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