ENSG00000137675


Homo sapiens

Features
Gene ID: ENSG00000137675
  
Biological name :MMP27
  
Synonyms : matrix metallopeptidase 27 / MMP27 / Q9H306
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q22.2
Gene start: 102691487
Gene end: 102705806
  
Corresponding Affymetrix probe sets: 220783_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000260229
NCBI entrez gene - 64066     See in Manteia.
RefSeq - XM_017018120
RefSeq - NM_022122
RefSeq - XM_011542949
RefSeq - XM_011542950
RefSeq - XM_011542948
RefSeq Peptide - NP_071405
swissprot - Q9H306
Ensembl - ENSG00000137675
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MMP27ENSGALG00000019060Gallus gallus
 Mmp27ENSMUSG00000070323Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MMP3 / P08254 / matrix metallopeptidase 3ENSG0000014996847
MMP10 / P09238 / matrix metallopeptidase 10ENSG0000016667047
MMP1 / P03956 / matrix metallopeptidase 1ENSG0000019661145
MMP8 / P22894 / matrix metallopeptidase 8ENSG0000011811344
MMP12 / P39900 / matrix metallopeptidase 12ENSG0000026240644
MMP13 / P45452 / matrix metallopeptidase 13ENSG0000013774544
MMP20 / O60882 / matrix metallopeptidase 20ENSG0000013767439
MMP24 / Q9Y5R2 / matrix metallopeptidase 24ENSG0000012596634
MMP15 / P51511 / matrix metallopeptidase 15ENSG0000010299634
MMP14 / P50281 / matrix metallopeptidase 14ENSG0000015722733
MMP16 / P51512 / matrix metallopeptidase 16ENSG0000015610333
MMP17 / Q9ULZ9 / matrix metallopeptidase 17ENSG0000019859831
MMP25 / Q9NPA2 / matrix metallopeptidase 25ENSG0000000851630
MMP11 / P24347 / matrix metallopeptidase 11ENSG0000009995329
MMP7 / P09237 / matrix metallopeptidase 7ENSG0000013767324


Protein motifs (from Interpro)
Interpro ID Name
 IPR000585  Hemopexin-like domain
 IPR001818  Peptidase M10, metallopeptidase
 IPR002477  Peptidoglycan binding-like
 IPR006026  Peptidase, metallopeptidase
 IPR018486  Hemopexin, conserved site
 IPR018487  Hemopexin-like repeats
 IPR021158  Peptidase M10A, cysteine switch, zinc binding site
 IPR021190  Peptidase M10A
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR028732  Matrix metalloproteinase-27
 IPR033739  Peptidase M10A, catalytic domain
 IPR036365  PGBD-like superfamily
 IPR036375  Hemopexin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0030574 collagen catabolic process IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0042406 extrinsic component of endoplasmic reticulum membrane IDA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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