ENSG00000198598


Homo sapiens

Features
Gene ID: ENSG00000198598
  
Biological name :MMP17
  
Synonyms : matrix metallopeptidase 17 / MMP17 / Q9ULZ9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q24.33
Gene start: 131828393
Gene end: 131851783
  
Corresponding Affymetrix probe sets: 206234_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000445620
Ensembl peptide - ENSP00000443727
Ensembl peptide - ENSP00000444603
Ensembl peptide - ENSP00000353767
Ensembl peptide - ENSP00000439542
Ensembl peptide - ENSP00000441106
Ensembl peptide - ENSP00000441710
Ensembl peptide - ENSP00000442104
NCBI entrez gene - 4326     See in Manteia.
OMIM - 602285
RefSeq - XM_017019307
RefSeq - NM_016155
RefSeq - XM_011538355
RefSeq - XM_011538356
RefSeq - XM_011538357
RefSeq Peptide - NP_057239
swissprot - F5GWR3
swissprot - Q9ULZ9
swissprot - F5GZA7
swissprot - F5H209
swissprot - F5H249
swissprot - F5H881
swissprot - F5H846
Ensembl - ENSG00000198598
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mmp17aENSDARG00000078915Danio rerio
 Mmp17ENSMUSG00000029436Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MMP25 / Q9NPA2 / matrix metallopeptidase 25ENSG0000000851643
MMP15 / P51511 / matrix metallopeptidase 15ENSG0000010299634
MMP14 / P50281 / matrix metallopeptidase 14ENSG0000015722732
MMP16 / P51512 / matrix metallopeptidase 16ENSG0000015610332
MMP24 / Q9Y5R2 / matrix metallopeptidase 24ENSG0000012596632
MMP3 / P08254 / matrix metallopeptidase 3ENSG0000014996829
MMP10 / P09238 / matrix metallopeptidase 10ENSG0000016667028
MMP11 / P24347 / matrix metallopeptidase 11ENSG0000009995328
MMP13 / P45452 / matrix metallopeptidase 13ENSG0000013774527
MMP1 / P03956 / matrix metallopeptidase 1ENSG0000019661126
MMP20 / O60882 / matrix metallopeptidase 20ENSG0000013767426
MMP8 / P22894 / matrix metallopeptidase 8ENSG0000011811326
MMP27 / Q9H306 / matrix metallopeptidase 27ENSG0000013767526
MMP12 / P39900 / matrix metallopeptidase 12ENSG0000026240625
MMP7 / P09237 / matrix metallopeptidase 7ENSG0000013767315


Protein motifs (from Interpro)
Interpro ID Name
 IPR000585  Hemopexin-like domain
 IPR001818  Peptidase M10, metallopeptidase
 IPR002477  Peptidoglycan binding-like
 IPR006026  Peptidase, metallopeptidase
 IPR018487  Hemopexin-like repeats
 IPR021190  Peptidase M10A
 IPR024079  Metallopeptidase, catalytic domain superfamily
 IPR028726  Matrix metalloproteinase-17
 IPR033739  Peptidase M10A, catalytic domain
 IPR036365  PGBD-like superfamily
 IPR036375  Hemopexin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0042756 drinking behavior IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0004222 metalloendopeptidase activity IEA
 molecular_functionGO:0008047 enzyme activator activity TAS
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070006 metalloaminopeptidase activity TAS


Pathways (from Reactome)
Pathway description
Activation of Matrix Metalloproteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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