MP:0000150 | abnormal rib morphology | "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311] |
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Allelic Composition: Insrtm1Khn/Insrtm1Khn,Leprtm1.1Chua/Leprtm1.1Chua,Tg(Pomc1-cre)16Lowl/0 Genetic Background: involves: 129 * 129S4/SvJae * 129S6/SvEvTac * C57BL/6J * FVB/N
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MP:0000154 | rib fusion | "appearance of one or more ribs as a single structure" [J:62022, J:62023] |
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Allelic Composition: DbnlGt(betageo)11Byg/DbnlGt(betageo)11Byg Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Gnai3tm1Lbi/Gnai3tm1Lbi Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: Gnai1tm1Drs/Gnai1+,Gnai3tm1Lbi/Gnai3tm1Lbi Genetic Background: involves: 129S/SvEv
Allelic Composition: Gnai2tm1Lbi/Gnai2+,Gnai3tm1Lbi/Gnai3tm1Lbi Genetic Background: involves: 129S/SvEv * 129S7/SvEvBrd
Allelic Composition: Gnai2tm2.1Lbi/Gnai2tm2.1Lbi,Gnai3tm1Lbi/Gnai3tm1Lbi,Sox9tm3(cre)Crm/Sox9+ Genetic Background: involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6
Allelic Composition: Gnai2tm2.1Lbi/Gnai2+,Gnai3tm1Lbi/Gnai3tm1Lbi,Sox9tm3(cre)Crm/Sox9+ Genetic Background: involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6
Allelic Composition: Gnai2tm2.1Lbi/Gnai2tm2.1Lbi,Gnai3tm1Lbi/Gnai3tm1Lbi,Tg(Myog-cre)1Eno/0 Genetic Background: involves: 129S/SvEv * C57BL/6
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MP:0002444 | abnormal T cell physiology | "anomalous response of T lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Gnai2tm1Lbi/Gnai2tm1Lbi Genetic Background: B6.129S7-Gnai2tm1Lbi
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MP:0003049 | abnormal lumbar vertebrae morphology | "malformation of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Gnai3tm1Lbi/Gnai3tm1Lbi Genetic Background: involves: 129S/SvEv * C57BL/6
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MP:0004621 | lumbar vertebral fusion | "the union of one or more lumbar vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: DbnlGt(betageo)11Byg/DbnlGt(betageo)11Byg Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Gnai3tm1Lbi/Gnai3tm1Lbi Genetic Background: involves: 129S/SvEv
Allelic Composition: Gnai1tm1Drs/Gnai1+,Gnai3tm1Lbi/Gnai3tm1Lbi Genetic Background: involves: 129S/SvEv
Allelic Composition: Gnai2tm2.1Lbi/Gnai2tm2.1Lbi,Gnai3tm1Lbi/Gnai3tm1Lbi,Sox9tm3(cre)Crm/Sox9+ Genetic Background: involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6
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MP:0008146 | asymmetric rib-sternum attachment | "loss of bilateral symmetry in rib attachments to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: DbnlGt(betageo)11Byg/DbnlGt(betageo)11Byg Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0008148 | abnormal rib-sternum attachment | "any anomaly in the in the normal joining of the ribs to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gnai3tm1Lbi/Gnai3tm1Lbi Genetic Background: involves: 129S/SvEv
Allelic Composition: Gnai2tm1Lbi/Gnai2+,Gnai3tm1Lbi/Gnai3tm1Lbi Genetic Background: involves: 129S/SvEv * 129S7/SvEvBrd
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MP:0008560 | increased tumor necrosis factor secretion | "increase in the production or release of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MESH:D12.644.276.374.500.800] |
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Allelic Composition: DbnlGt(betageo)11Byg/DbnlGt(betageo)11Byg Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0008661 | decreased interleukin-10 secretion | "reduction in the production or release of a cytokine produced by a variety of cell types, including T-cells, monocytes, dendritic cells and epithelial cells that exerts a variety of effects on immunoregulation and inflammation" [MESH:D12.644.276.374.465.510] |
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Allelic Composition: DbnlGt(betageo)11Byg/DbnlGt(betageo)11Byg Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009818 | abnormal thromboxane level | |
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Allelic Composition: DbnlGt(betageo)11Byg/DbnlGt(betageo)11Byg Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0010082 | sternebra fusion | "appearance of one or more sternebrae as a single structure" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: DbnlGt(betageo)11Byg/DbnlGt(betageo)11Byg Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Gnai1tm1Drs/Gnai1+,Gnai3tm1Lbi/Gnai3tm1Lbi Genetic Background: involves: 129S/SvEv
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