ENSG00000106852


Homo sapiens

Features
Gene ID: ENSG00000106852
  
Biological name :LHX6
  
Synonyms : LHX6 / LIM homeobox 6 / Q9UPM6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q33.2
Gene start: 122202577
Gene end: 122229626
  
Corresponding Affymetrix probe sets: 219884_at (Human Genome U133 Plus 2.0 Array)   224556_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000453798
Ensembl peptide - ENSP00000453606
Ensembl peptide - ENSP00000475927
Ensembl peptide - ENSP00000340137
Ensembl peptide - ENSP00000362859
Ensembl peptide - ENSP00000362860
Ensembl peptide - ENSP00000377854
Ensembl peptide - ENSP00000441464
Ensembl peptide - ENSP00000452811
NCBI entrez gene - 26468     See in Manteia.
OMIM - 608215
RefSeq - XM_011518522
RefSeq - NM_001242333
RefSeq - NM_001242334
RefSeq - NM_001242335
RefSeq - NM_001348190
RefSeq - NM_014368
RefSeq - NM_199160
RefSeq - XM_011518521
RefSeq Peptide - NP_001229262
RefSeq Peptide - NP_001229264
RefSeq Peptide - NP_001335119
RefSeq Peptide - NP_055183
RefSeq Peptide - NP_954629
RefSeq Peptide - NP_001229263
swissprot - H0YMH3
swissprot - A0A024R852
swissprot - H0YKH7
swissprot - Q9UPM6
swissprot - H0YMY8
Ensembl - ENSG00000106852
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lhx6ENSDARG00000006896Danio rerio
 si:ch211-236k19.2ENSDARG00000052165Danio rerio
 LHX6ENSGALG00000001347Gallus gallus
 Lhx6ENSMUSG00000026890Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LHX8 / Q68G74 / LIM homeobox 8ENSG0000016262450
LHX2 / P50458 / LIM homeobox 2ENSG0000010668929
LHX9 / Q9NQ69 / LIM homeobox 9ENSG0000014335529
LHX3 / Q9UBR4 / LIM homeobox 3ENSG0000010718725
LMX1B / O60663 / LIM homeobox transcription factor 1 betaENSG0000013694425
LHX5 / Q9H2C1 / LIM homeobox 5ENSG0000008911624
LMX1A / Q8TE12 / LIM homeobox transcription factor 1 alphaENSG0000016276124
ISL2 / Q96A47 / ISL LIM homeobox 2ENSG0000015955624
LHX1 / P48742 / LIM homeobox 1ENSG0000027370624
ISL1 / P61371 / ISL LIM homeobox 1ENSG0000001608224
LHX4 / Q969G2 / LIM homeobox 4ENSG0000012145423
LMO4 / P61968 / LIM domain only 4ENSG0000014301315
LMO1 / P25800 / LIM domain only 1ENSG0000016640714
LMO3 / Q8TAP4 / LIM domain only 3ENSG0000004854012
LMO2 / P25791 / LIM domain only 2ENSG0000013536311


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001781  Zinc finger, LIM-type
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0021799 cerebral cortex radially oriented cell migration ISS
 biological_processGO:0021800 cerebral cortex tangential migration ISS
 biological_processGO:0021853 cerebral cortex GABAergic interneuron migration ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0048469 cell maturation ISS
 cellular_componentGO:0005634 nucleus IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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