ENSG00000143355


Homo sapiens

Features
Gene ID: ENSG00000143355
  
Biological name :LHX9
  
Synonyms : LHX9 / LIM homeobox 9 / Q9NQ69
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q31.3
Gene start: 197911902
Gene end: 197935478
  
Corresponding Affymetrix probe sets: 1560253_at (Human Genome U133 Plus 2.0 Array)   1562736_at (Human Genome U133 Plus 2.0 Array)   1565406_a_at (Human Genome U133 Plus 2.0 Array)   1565407_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356361
Ensembl peptide - ENSP00000483170
Ensembl peptide - ENSP00000482898
Ensembl peptide - ENSP00000453064
Ensembl peptide - ENSP00000356357
Ensembl peptide - ENSP00000356358
Ensembl peptide - ENSP00000356360
NCBI entrez gene - 56956     See in Manteia.
OMIM - 606066
RefSeq - XM_017001849
RefSeq - NM_001014434
RefSeq - NM_020204
RefSeq - XM_005245350
RefSeq - XM_011509781
RefSeq Peptide - NP_001014434
RefSeq Peptide - NP_064589
swissprot - H0Y330
swissprot - H0YL54
swissprot - Q9NQ69
swissprot - A0A087X083
swissprot - A0A0C4DGY4
Ensembl - ENSG00000143355
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lhx9ENSDARG00000056979Danio rerio
 LHX9ENSGALG00000002223Gallus gallus
 Lhx9ENSMUSG00000019230Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LHX2 / P50458 / LIM homeobox 2ENSG0000010668970
LHX8 / Q68G74 / LIM homeobox 8ENSG0000016262428
LHX6 / Q9UPM6 / LIM homeobox 6ENSG0000010685228
ISL2 / Q96A47 / ISL LIM homeobox 2ENSG0000015955626
LHX5 / Q9H2C1 / LIM homeobox 5ENSG0000008911625
LHX1 / P48742 / LIM homeobox 1ENSG0000027370625
LMX1B / O60663 / LIM homeobox transcription factor 1 betaENSG0000013694425
ISL1 / P61371 / ISL LIM homeobox 1ENSG0000001608224
LMX1A / Q8TE12 / LIM homeobox transcription factor 1 alphaENSG0000016276124
LHX3 / Q9UBR4 / LIM homeobox 3ENSG0000010718723
LHX4 / Q969G2 / LIM homeobox 4ENSG0000012145422
LMO4 / P61968 / LIM domain only 4ENSG0000014301316
LMO1 / P25800 / LIM domain only 1ENSG0000016640715
LMO3 / Q8TAP4 / LIM domain only 3ENSG0000004854014
LMO2 / P25791 / LIM domain only 2ENSG0000013536312


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001781  Zinc finger, LIM-type
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0008585 female gonad development IEA
 biological_processGO:0035262 gonad morphogenesis IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0097380 dorsal spinal cord interneuron anterior axon guidance ISS
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003714 transcription corepressor activity ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Regulation of expression of SLITs and ROBOs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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