ENSG00000162624


Homo sapiens

Features
Gene ID: ENSG00000162624
  
Biological name :LHX8
  
Synonyms : LHX8 / LIM homeobox 8 / Q68G74
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p31.1
Gene start: 75128434
Gene end: 75161533
  
Corresponding Affymetrix probe sets: 1569469_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000294638
Ensembl peptide - ENSP00000348597
NCBI entrez gene - 431707     See in Manteia.
OMIM - 604425
RefSeq - XM_017001317
RefSeq - NM_001001933
RefSeq - NM_001256114
RefSeq - XM_017001316
RefSeq Peptide - NP_001001933
RefSeq Peptide - NP_001243043
swissprot - Q68G74
Ensembl - ENSG00000162624
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lhx8aENSDARG00000002330Danio rerio
 lhx8bENSDARG00000042145Danio rerio
 LHX8ENSGALG00000011369Gallus gallus
 Lhx8ENSMUSG00000096225Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LHX6 / Q9UPM6 / LIM homeobox 6ENSG0000010685255
LHX9 / Q9NQ69 / LIM homeobox 9ENSG0000014335532
LHX2 / P50458 / LIM homeobox 2ENSG0000010668930
LMX1B / O60663 / LIM homeobox transcription factor 1 betaENSG0000013694429
LMX1A / Q8TE12 / LIM homeobox transcription factor 1 alphaENSG0000016276128
LHX3 / Q9UBR4 / LIM homeobox 3ENSG0000010718727
LHX4 / Q969G2 / LIM homeobox 4ENSG0000012145427
ISL1 / P61371 / ISL LIM homeobox 1ENSG0000001608226
LHX1 / P48742 / LIM homeobox 1ENSG0000027370626
ISL2 / Q96A47 / ISL LIM homeobox 2ENSG0000015955625
LHX5 / Q9H2C1 / LIM homeobox 5ENSG0000008911624
LMO4 / P61968 / LIM domain only 4ENSG0000014301316
LMO1 / P25800 / LIM domain only 1ENSG0000016640714
LMO3 / Q8TAP4 / LIM domain only 3ENSG0000004854013
LMO2 / P25791 / LIM domain only 2ENSG0000013536312


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR001781  Zinc finger, LIM-type
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007611 learning or memory IEA
 biological_processGO:0008585 female gonad development IEA
 biological_processGO:0021879 forebrain neuron differentiation IEA
 biological_processGO:0021884 forebrain neuron development IEA
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IEA
 cellular_componentGO:0001674 female germ cell nucleus IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr