ENSG00000175189


Homo sapiens

Features
Gene ID: ENSG00000175189
  
Biological name :INHBC
  
Synonyms : INHBC / inhibin beta C subunit / P55103
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q13.3
Gene start: 57434760
Gene end: 57450828
  
Corresponding Affymetrix probe sets: 207687_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000308716
NCBI entrez gene - 3626     See in Manteia.
OMIM - 601233
RefSeq - NM_005538
RefSeq Peptide - NP_005529
swissprot - P55103
Ensembl - ENSG00000175189
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 INHBEENSDARG00000100986Danio rerio
 InhbcENSMUSG00000025405Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
INHBE / P58166 / inhibin beta E subunitENSG0000013926941
INHBB / P09529 / inhibin beta B subunitENSG0000016308338
INHBA / P08476 / inhibin beta A subunitENSG0000012264136
GDF11 / O95390 / growth differentiation factor 11ENSG0000013541424
MSTN / O14793 / myostatinENSG0000013837921
GDF1 / P27539 / growth differentiation factor 1ENSG0000013028320
TGFB3 / P10600 / transforming growth factor beta 3ENSG0000011969920
TGFB1 / P01137 / transforming growth factor beta 1ENSG0000010532920
CERS1 / P27544 / ceramide synthase 1ENSG0000022380220
GDF3 / Q9NR23 / growth differentiation factor 3ENSG0000018434419
GDF10 / P55107 / growth differentiation factor 10ENSG0000026652418
TGFB2 / P61812 / transforming growth factor beta 2ENSG0000009296918
NODAL / Q96S42 / nodal growth differentiation factorENSG0000015657417
BMP3 / P12645 / bone morphogenetic protein 3ENSG0000015278516
BMP15 / O95972 / bone morphogenetic protein 15ENSG0000013038516
GDF9 / O60383 / growth differentiation factor 9ENSG0000016440415
GDF15 / Q99988 / growth differentiation factor 15ENSG0000013051313


Protein motifs (from Interpro)
Interpro ID Name
 IPR001318  Inhibin, beta C subunit
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0060395 SMAD protein signal transduction IBA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding TAS
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Glycoprotein hormones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000122641 INHBA / P08476 / inhibin beta A subunit  / complex
 ENSG00000123999 INHA / P05111 / inhibin alpha subunit  / complex
 ENSG00000139269 INHBE / P58166 / inhibin beta E subunit  / complex
 ENSG00000163083 INHBB / P09529 / inhibin beta B subunit  / complex
 ENSG00000175189 INHBC / P55103 / inhibin beta C subunit  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr