ENSMUSG00000021061


Mus musculus

Features
Gene ID: ENSMUSG00000021061
  
Biological name :Sptb
  
Synonyms : spectrin beta, erythrocytic / Sptb
  
Possible biological names infered from orthology : P11277
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: C3
Gene start: 76580488
Gene end: 76710547
  
Corresponding Affymetrix probe sets: 10401068 (MoGene1.0st)   1450556_at (Mouse Genome 430 2.0 Array)   1455226_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000129782
Ensembl peptide - ENSMUSP00000021458
NCBI entrez gene - 20741     See in Manteia.
MGI - MGI:98387
RefSeq - NM_013675
RefSeq Peptide - NP_038703
swissprot - E9Q397
swissprot - Q3UGX2
Ensembl - ENSMUSG00000021061
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sptbENSDARG00000030490Danio rerio
 SPTBENSGALG00000036805Gallus gallus
 SPTBENSG00000070182Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q62261 / Sptbn1 / Spectrin beta chain, non-erythrocytic 1 / Q01082* / spectrin beta, non-erythrocytic 1*ENSMUSG0000002031559
Sptbn2 / spectrin beta, non-erythrocytic 2 / O15020*ENSMUSG0000006788952
Sptbn4 / spectrin beta, non-erythrocytic 4 / Q9H254*ENSMUSG0000001175148
P16546 / Sptan1 / Spectrin alpha chain, non-erythrocytic 1 / Q13813* / spectrin alpha, non-erythrocytic 1*ENSMUSG0000005773822
Spta1 / P08032 / Spectrin alpha chain, erythrocytic 1 / P02549* / spectrin alpha, erythrocytic 1*ENSMUSG0000002653220
Actn4 / P57780 / Alpha-actinin-4 / O43707* / actinin alpha 4*ENSMUSG0000005480811
Actn1 / Q7TPR4 / Mus musculus actinin, alpha 1 (Actn1), transcript variant 2, mRNA. / P12814* / actinin alpha 1*ENSMUSG0000001514311
Actn2 / Q9JI91 / Alpha-actinin-2 / P35609* / actinin alpha 2*ENSMUSG0000005237411
Actn3 / O88990 / Alpha-actinin-3 / Q08043* / actinin alpha 3 (gene/pseudogene)*ENSMUSG0000000645711


Protein motifs (from Interpro)
Interpro ID Name
 IPR001589  Actinin-type actin-binding domain, conserved site
 IPR001605  Pleckstrin homology domain, spectrin-type
 IPR001715  Calponin homology domain
 IPR001849  Pleckstrin homology domain
 IPR002017  Spectrin repeat
 IPR011993  PH-like domain superfamily
 IPR016343  Spectrin, beta subunit
 IPR018159  Spectrin/alpha-actinin
 IPR036872  CH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007010 cytoskeleton organization IEA
 biological_processGO:0051693 actin filament capping IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0008091 spectrin IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005200 structural constituent of cytoskeleton IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005543 phospholipid binding IEA


Pathways (from Reactome)
Pathway description
NCAM signaling for neurite out-growth
Interaction between L1 and Ankyrins
RAF/MAP kinase cascade
COPI-mediated anterograde transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000208 decreased hematocrit "less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0000240 extramedullary hematopoiesis "formation and development of blood cells outside the bone marrow, e.g., in the spleen, liver, or lymph nodes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih
Genetic Background: involves: 129S/SvEv

Allelic Composition: Sptbm1Jus/Sptbm1Jus
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0000314 schistocytosis "the appearance of poikilocytes in the blood that owe their abnormal shape to fragmentation occurring as the cells flow through damaged small vessels" [J:82330, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0000519 hydronephrosis "dilation of the pelvis and calices of one or both kidneys" [J:56641]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0000599 enlarged liver "larger than average size of the liver" [J:65146]
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih
Genetic Background: involves: 129S/SvEv

Allelic Composition: Sptbm1Jus/Sptbm1Jus
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0000611 jaundice "clinical manifestation of hyperbilirubinemia, with deposition of bile pigments in the skin, resulting in yellowish staining of the skin and mucous membranes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih
Genetic Background: involves: 129S/SvEv

Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0000691 enlarged spleen "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih
Genetic Background: involves: 129S/SvEv

Allelic Composition: Sptbm1Jus/Sptbm1Jus
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+,Lin9tm1.1Sgau/Lin9tm1.1Sgau
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL

 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
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Allelic Composition: Map1btm1Noh/Map1btm1Noh,Map2tm1Noh/Map2tm1Noh
Genetic Background: involves: C57BL/6

Allelic Composition: Sptbm1Jus/Sptbm1Jus
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001585 hemolytic anemia "an anemic condition resulting from an increased rate of erythrocyte destruction" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih
Genetic Background: involves: 129S/SvEv

Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0001625 cardiac hypertrophy "an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0001655 multifocal hepatic necrosis "multiple localized areas of pathologic death of cells within, or portions of, the liver" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih
Genetic Background: involves: 129S/SvEv

 MP:0001924 infertility "inability to produce live offspring" [J:47225]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+,Lin9tm1.1Sgau/Lin9tm1.1Sgau
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL

 MP:0002152 abnormal brain morphology "anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0002424 abnormal reticulocyte morphology/development "anomalous structure, formation, or numbers of immature erthrocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih
Genetic Background: involves: 129S/SvEv

 MP:0002447 abnormal erythrocyte morphology "structural anomaly of the cells in the blood that carry oxygen, red blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Sptbm1Jus/Sptbm1Jus
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0002594 low mean erythrocyte count "less than average numbers of red blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0002640 reticulocytosis "an increase in the number of reticulocytes in the blood" [J:78271, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih
Genetic Background: involves: 129S/SvEv

Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0002641 anisopoikilocytosis "presence in blood of RBCs of abnormal shapes and sizes" [J:78271, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0002642 anisocytosis "blood cells of variable size on smear" [J:7209, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih
Genetic Background: involves: 129S/SvEv

 MP:0002643 poikilocytosis "blood cells of variable shape on smear" [J:7209, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih
Genetic Background: involves: 129S/SvEv

Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0002704 tubular nephritis "inflammation of the renal tubules" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0002743 glomerulonephritis "glomerular disease characterized by diffuse inflammatory reaction that is not the acute response to infection of the kidneys" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0002812 spherocytosis "the presence of sphere-shaped erythrocytes in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Sptbm1Jus/Sptbm1Jus
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0002813 microcytosis "the presence of unusually small erythrocytes in the circulating blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0002874 decreased hemoglobin content "decrease in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0002875 decreased erythrocyte count "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0003068 enlarged kidney "larger than average size of the kidney" [J:86005, pvb:Pierre Vanden Borre, Mouse Genome Informatics Curator]
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Allelic Composition: Sptbm1Jus/Sptbm1Jus
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0003656 abnormal erythrocyte physiology "functional anomaly of the cells in the blood that carry oxygen, red blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0003657 abnormal erythrocyte lysis "increase or decrease in the ability of RBCs to withstand changes in osmolarity" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Sptbm1Jus/Sptbm1Jus
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

Allelic Composition: Sptbja/Sptb+
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0004154 renal tubular necrosis "pathological cell death in the proximal and/or distal renal tubules, usually due to irreversible damage " [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0005329 abnormal cardiac muscle morphology "anomalous structure of the involuntary muscle comprising the myocardium " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0005344 increased circulating bilirubin level "greater than the normal concentration in the blood of this yellow heme breakdown product" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0005360 urolithiasis "presence of calculi in any part of the urinary system" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:85461, J:85462]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0008476 increased spleen red pulp amount "increase in the quantity of the parenchymatous tissue network of the spleen that consists of loose plates or cords (sinuses) infiltrated with red blood cells where most of the blood filtration occurs and degenerate erythrocytes are removed from the circulation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0008810 increased circulating iron level "elevation in the concentration of iron in the blood" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0008956 decreased cellular hemoglobin content "decrease in the mean of the red blood cell hemoglobin concentration (RBC CH) histogram, which represents the distribution of red blood cells by the amount of hemoglobin present in each individual cell independent of cell volume" [MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0009395 persistence of primitive erythrocytes "presence of increased numbers of nucleated red blood cells at stages when these cells are normally replaced by mature, enucleated, red blood cells" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0010025 decreased total body fat amount "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0010035 increased erythrocyte clearance "increased elimination of aging erythrocytes from the body by autoregulatory mechanisms, often expressed as half-life" [GO:0034102, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

Allelic Composition: Sptbja/Sptb+
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0010163 hemolysis "destruction of erythrocytes such that hemoglobin is released from the cells; may occur by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0010177 acanthocytosis "presence of erythrocytes characterized by multiple spiny (thorn-like) cytoplasmic projections" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Sptbm1Jus/Sptbm1Jus
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0010375 increased kidney iron level "increase in the amount of iron present in the renal tissue" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih
Genetic Background: involves: 129S/SvEv

Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Cyp19a1tm1Sih/Cyp19a1tm1Sih
Genetic Background: involves: 129S/SvEv

 MP:0011188 increased erythrocyte protoporphyrin level "an accumulation of the intermediates of heme biosynthesis in red blood cells" [MGI:csmith]
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Allelic Composition: Map1btm1Noh/Map1btm1Noh,Map2tm1Noh/Map2tm1Noh
Genetic Background: involves: C57BL/6

Allelic Composition: Sptbja/Sptbja
Genetic Background: involves: 129/Sv * C57BL/6J * WB/Re

Allelic Composition: Sptbja/Sptb+
Genetic Background: involves: 129/Sv * C57BL/6J * WB/Re

 MP:0020409 abnormal cardiac thrombosis "any anomaly in the formation or presence of thrombi in the heart" [PMID:15870284]
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Allelic Composition: Sptbja/Sptbja
Genetic Background: (WB.129-Sptbja/J x B6.129-Sptbja/J)F1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020315 Q62261 / Sptbn1 / Spectrin beta chain, non-erythrocytic 1 / Q01082* / spectrin beta, non-erythrocytic 1*  / complex
 ENSMUSG00000067889 Sptbn2 / spectrin beta, non-erythrocytic 2 / O15020*  / complex
 ENSMUSG00000059923 Grb2 / Q60631 / Growth factor receptor-bound protein 2 / P62993*  / reaction / complex
 ENSMUSG00000011751 Sptbn4 / spectrin beta, non-erythrocytic 4 / Q9H254*  / complex
 ENSMUSG00000026532 Spta1 / P08032 / Spectrin alpha chain, erythrocytic 1 / P02549* / spectrin alpha, erythrocytic 1*  / complex
 ENSMUSG00000032826 Ank2 / Q8C8R3 / Ankyrin-2 / Q01484*  / complex / reaction
 ENSMUSG00000021061 Sptb / spectrin beta, erythrocytic / P11277*  / complex
 ENSMUSG00000031543 Ank1 / Q02357 / Ankyrin-1 / P16157*  / reaction / complex
 ENSMUSG00000027303 Ptpra / P18052 / protein tyrosine phosphatase, receptor type, A / P18433*  / complex
 ENSMUSG00000062825 Actg1 / P63260 / Actin, cytoplasmic 2 Actin, cytoplasmic 2, N-terminally processed / P63261* / actin gamma 1*  / complex
 ENSMUSG00000024241 Sos1 / Q62245 / Son of sevenless homolog 1 / Q07889* / SOS Ras/Rac guanine nucleotide exchange factor 1*  / complex / reaction
 ENSMUSG00000057738 P16546 / Sptan1 / Spectrin alpha chain, non-erythrocytic 1 / Q13813* / spectrin alpha, non-erythrocytic 1*  / complex
 ENSMUSG00000019843 Fyn / P39688 / Tyrosine-protein kinase Fyn / P06241* / FYN proto-oncogene, Src family tyrosine kinase*  / complex
 ENSMUSG00000029580 Actb / P60710 / Actin, cytoplasmic 1 Actin, cytoplasmic 1, N-terminally processed / POTEJ* / P60709* / P0CG39* / actin beta* / POTE ankyrin domain family member J*  / complex
 ENSMUSG00000022607 Ptk2 / P34152 / PTK2 protein tyrosine kinase 2 / Q05397* / protein tyrosine kinase 2*  / complex






 

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