ENSDARG00000012426


Danio rerio

Features
Gene ID: ENSDARG00000012426
  
Biological name :neflb
  
Synonyms : neflb / neurofilament, light polypeptide b
  
Possible biological names infered from orthology : NEFL / neurofilament light / Neurofilament light polypeptide / P07196 / P08551
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 6873853
Gene end: 6877390
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000017029
Ensembl peptide - ENSDARP00000141955
NCBI entrez gene - 664698     See in Manteia.
RefSeq - NM_001039838
RefSeq Peptide - NP_001034927
swissprot - B0R1B8
swissprot - A0A0R4IZ96
ZFIN ID - ZDB-GENE-060312-44
Ensembl - ENSDARG00000012426
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NEFLENSGALG00000000314Gallus gallus
 NEFLENSG00000277586Homo sapiens
 NeflENSMUSG00000022055Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nefla / neurofilament, light polypeptide a / NEFL* / P08551* / P07196* / neurofilament light* / Neurofilament light polypeptide *ENSDARG0000005756856
zgc:65851ENSDARG0000001228140
inaa / internexin neuronal intermediate filament protein, alpha a / INA* / Q16352* / P46660* / internexin neuronal intermediate filament protein alpha*ENSDARG0000001186235
nefma / neurofilament, medium polypeptide a / NEFM* / P07197* / neurofilament medium*ENSDARG0000002135134
nefmb / neurofilament, medium polypeptide b / NEFM* / P07197* / neurofilament medium*ENSDARG0000004369734
inab / internexin neuronal intermediate filament protein, alpha b / INA* / Q16352* / P46660* / internexin neuronal intermediate filament protein alpha*ENSDARG0000005324834
desma / desmin a / DES* / desmin* / P17661* / P31001*ENSDARG0000005865632
desmb / desmin b / DES* / desmin* / P17661* / P31001*ENSDARG0000000522132
viml / vimentin like / VIM* / P08670* / vimentin*ENSDARG0000004450131
vim / vimentin / P08670* / P20152*ENSDARG0000001000831
prph / peripherin / P41219*ENSDARG0000002830629
gfap / glial fibrillary acidic protein / P03995* / P14136*ENSDARG0000002530129
si:dkey-33c12.3ENSDARG0000005788128
ngs / notochord granular surfaceENSDARG0000005432126
zgc:172323ENSDARG0000005320125
si:dkey-27m7.4ENSDARG0000000314622
lmnb2 / lamin B2 / P21619* / Q03252*ENSDARG0000010162421
lmnb1 / lamin B1 / P14733* / P20700*ENSDARG0000004429920
lmna / lamin A / P02545* / P48678* / lamin A/C* / Prelamin-A/C Lamin-A/C*ENSDARG0000001341519
zgc:136930ENSDARG0000005519217


Protein motifs (from Interpro)
Interpro ID Name
 IPR001664  Intermediate filament protein
 IPR002957  Keratin, type I
 IPR006821  Intermediate filament head, DNA-binding domain
 IPR018039  Intermediate filament protein, conserved site
 IPR027692  Neurofilament light polypeptide


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0061564 axon development IEA
 cellular_componentGO:0005882 intermediate filament IEA
 cellular_componentGO:0005883 neurofilament IEA
 molecular_functionGO:0005198 structural molecule activity IEA


Pathways (from Reactome)
Pathway description
Unblocking of NMDA receptor, glutamate binding and activation
CREB phosphorylation through the activation of CaMKII
Ras activation upon Ca2+ influx through NMDA receptor
RAF/MAP kinase cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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