ENSG00000033122


Homo sapiens

Features
Gene ID: ENSG00000033122
  
Biological name :LRRC7
  
Synonyms : leucine rich repeat containing 7 / LRRC7 / Q96NW7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p31.1
Gene start: 69568398
Gene end: 70151945
  
Corresponding Affymetrix probe sets: 1552666_a_at (Human Genome U133 Plus 2.0 Array)   1566449_at (Human Genome U133 Plus 2.0 Array)   233499_at (Human Genome U133 Plus 2.0 Array)   239767_at (Human Genome U133 Plus 2.0 Array)   242050_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000476307
Ensembl peptide - ENSP00000466082
Ensembl peptide - ENSP00000476660
Ensembl peptide - ENSP00000477399
Ensembl peptide - ENSP00000035383
Ensembl peptide - ENSP00000309245
Ensembl peptide - ENSP00000359997
Ensembl peptide - ENSP00000394867
NCBI entrez gene - 57554     See in Manteia.
OMIM - 614453
RefSeq - XM_017001895
RefSeq - NM_020794
RefSeq - XM_017001885
RefSeq - XM_017001886
RefSeq - XM_017001887
RefSeq - XM_017001888
RefSeq - XM_017001889
RefSeq - XM_017001890
RefSeq - XM_017001891
RefSeq - XM_017001892
RefSeq - XM_017001893
RefSeq - XM_017001894
RefSeq - NM_001350216
RefSeq Peptide - NP_001317564
RefSeq Peptide - NP_001337145
RefSeq Peptide - NP_065845
swissprot - V9GZ42
swissprot - A0A075B6E9
swissprot - Q96NW7
swissprot - V9GY23
swissprot - B1AKT2
swissprot - V9GYE1
swissprot - F8WE45
swissprot - K7ELH5
Ensembl - ENSG00000033122
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrc7ENSDARG00000079670Danio rerio
 LRRC7ENSGALG00000011284Gallus gallus
 Lrrc7ENSMUSG00000028176Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ERBIN / Q96RT1 / erbb2 interacting proteinENSG0000011285139
SCRIB / Q14160 / scribbled planar cell polarity proteinENSG0000018090022
LRRC1 / Q9BTT6 / leucine rich repeat containing 1ENSG0000013726914
MFHAS1 / Q9Y4C4 / malignant fibrous histiocytoma amplified sequence 1ENSG0000014732412
LRRD1 / A4D1F6 / leucine rich repeats and death domain containing 1ENSG0000024072011
A6NIV6 / LRRIQ4 / leucine rich repeats and IQ motif containing 4ENSG000001883069
LRRC40 / Q9H9A6 / leucine rich repeat containing 40ENSG000000665579
SHOC2 / Q9UQ13 / SHOC2, leucine rich repeat scaffold proteinENSG000001080619
LRRC10 / Q5BKY1 / leucine rich repeat containing 10ENSG000001988125
A6NIK2 / LRRC10B / leucine rich repeat containing 10BENSG000002049505
A6NM36 / LRRC30 / leucine rich repeat containing 30ENSG000002064224


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0010976 positive regulation of neuron projection development IBA
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0014069 postsynaptic density IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0035580 specific granule lumen TAS
 cellular_componentGO:0043005 neuron projection IBA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000077522 ACTN2 / P35609 / actinin alpha 2  / complex
 ENSG00000082458 DLG3 / Q92796 / discs large MAGUK scaffold protein 3  / complex
 ENSG00000145349 CAMK2D / Q13557 / calcium/calmodulin dependent protein kinase II delta  / reaction / complex
 ENSG00000277586 NEFL / P07196 / neurofilament light  / complex
 ENSG00000132535 DLG4 / P78352 / discs large MAGUK scaffold protein 4  / complex
 ENSG00000174775 HRAS / P01112 / HRas proto-oncogene, GTPase  / reaction
 ENSG00000148660 CAMK2G / Q13555 / calcium/calmodulin dependent protein kinase II gamma  / reaction / complex
 ENSG00000070808 CAMK2A / Q9UQM7 / calcium/calmodulin dependent protein kinase II alpha  / reaction / complex
 ENSG00000183454 GRIN2A / Q12879 / glutamate ionotropic receptor NMDA type subunit 2A  / complex
 ENSG00000176884 GRIN1 / Q05586 / glutamate ionotropic receptor NMDA type subunit 1  / complex
 ENSG00000150672 DLG2 / Q15700 / discs large MAGUK scaffold protein 2  / complex
 ENSG00000075711 DLG1 / Q12959 / discs large MAGUK scaffold protein 1  / complex
 ENSG00000273079 GRIN2B / Q13224 / glutamate ionotropic receptor NMDA type subunit 2B  / complex
 ENSG00000058404 CAMK2B / Q13554 / calcium/calmodulin dependent protein kinase II beta  / reaction / complex
 ENSG00000113319 O14827 / RASGRF2 / Ras protein specific guanine nucleotide releasing factor 2  / complex / reaction
 ENSG00000120251 GRIA2 / P42262 / glutamate ionotropic receptor AMPA type subunit 2  / reaction
 ENSG00000155511 GRIA1 / P42261 / glutamate ionotropic receptor AMPA type subunit 1  / reaction
 ENSG00000152578 GRIA4 / P48058 / glutamate ionotropic receptor AMPA type subunit 4  / reaction
 ENSG00000198668 CALM1 / P0DP23 / calmodulin 1  / reaction / complex
 ENSG00000058335 Q13972 / RASGRF1 / Ras protein specific guanine nucleotide releasing factor 1  / reaction / complex
 ENSG00000125675 GRIA3 / P42263 / glutamate ionotropic receptor AMPA type subunit 3  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr