ENSMUSG00000047492


Mus musculus

Features
Gene ID: ENSMUSG00000047492
  
Biological name :Inhbe
  
Synonyms : Inhbe / Inhibin beta E chain / O08717
  
Possible biological names infered from orthology : inhibin beta E subunit / P58166
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: D3
Gene start: 127348857
Gene end: 127354411
  
Corresponding Affymetrix probe sets: 10373192 (MoGene1.0st)   1422144_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000053977
NCBI entrez gene - 16326     See in Manteia.
MGI - MGI:109269
RefSeq - NM_008382
RefSeq Peptide - NP_032408
swissprot - O08717
Ensembl - ENSMUSG00000047492
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 INHBEENSDARG00000100986Danio rerio
 INHBEENSG00000139269Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Inhbc / P55104 / Inhibin beta C chain / P55103* / inhibin beta C subunit*ENSMUSG0000002540538
Inhba / Q04998 / Inhibin beta A chain / P08476* / inhibin beta A subunit*ENSMUSG0000004132433
Inhbb / Q04999 / Inhibin beta B chain / P09529* / inhibin beta B subunit*ENSMUSG0000003703531
Gdf11 / Q9Z1W4 / Growth/differentiation factor 11 / O95390*ENSMUSG0000002535224
Tgfb1 / P04202 / transforming growth factor, beta 1 / P01137*ENSMUSG0000000260323
Nodal / P43021 / Q96S42* / nodal growth differentiation factor*ENSMUSG0000003717123
Tgfb2 / P27090 / Transforming growth factor beta-2 Latency-associated peptide / P61812* / transforming growth factor beta 2*ENSMUSG0000003923923
Mstn / O08689 / myostatin / O14793*ENSMUSG0000002610022
Tgfb3 / transforming growth factor, beta 3 / P10600*ENSMUSG0000002125322
Cers1 / P20863 / P27545 / Ceramide synthase 1 / GDF1* / P27539* / P27544* / growth differentiation factor 1*ENSMUSG0000008740820
Gdf1 / P20863 / Embryonic growth/differentiation factor 1 / CERS1* / P27544* / P27539* / ceramide synthase 1* / growth differentiation factor 1*ENSMUSG0000010952320
Gdf3 / Q07104 / Growth/differentiation factor 3 / Q9NR23*ENSMUSG0000003011719
Gdf10 / P97737 / Growth/differentiation factor 10 / P55107*ENSMUSG0000002194319
Bmp15 / Q9Z0L4 / Bone morphotic protein 15 / O95972* / bone morphogenetic protein 15*ENSMUSG0000002327917
Gdf9 / Q07105 / Growth/differentiation factor 9 / O60383*ENSMUSG0000001823815
Gdf15 / Q9Z0J7 / Mus musculus growth differentiation factor 15 (Gdf15), transcript variant 2, mRNA. / Q99988* / growth differentiation factor 15*ENSMUSG0000003850814
Bmp3 / Q8BHE5 / Bone morphotic protein 3 / P12645* / bone morphogenetic protein 3*ENSMUSG0000002933513


Protein motifs (from Interpro)
Interpro ID Name
 IPR001318  Inhibin, beta C subunit
 IPR001839  Transforming growth factor-beta, C-terminal
 IPR015615  Transforming growth factor-beta-related
 IPR017948  Transforming growth factor beta, conserved site
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043408 regulation of MAPK cascade IBA
 biological_processGO:0048468 cell development IBA
 biological_processGO:0060395 SMAD protein signal transduction IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IBA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Glycoprotein hormones


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rp1tm1Eap/Rp1tm1Eap
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Inhbetm2Zuk/Inhbetm2Zuk
Genetic Background: either: (involves: 129S5/SvEvBrd * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)

Allelic Composition: Inhbe/Inhbctm1Sjl/Inhbe/Inhbctm1Sjl
Genetic Background: B6.129-Inhbe/Inhbctm1Sjl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000037035 Inhbb / Q04999 / Inhibin beta B chain / P09529* / inhibin beta B subunit*  / complex
 ENSMUSG00000047492 Inhbe / O08717 / Inhibin beta E chain / P58166* / inhibin beta E subunit*  / complex
 ENSMUSG00000032968 Inha / Q04997 / Inhibin alpha chain / P05111* / inhibin alpha subunit*  / complex
 ENSMUSG00000041324 Inhba / Q04998 / Inhibin beta A chain / P08476* / inhibin beta A subunit*  / complex
 ENSMUSG00000025405 Inhbc / P55104 / Inhibin beta C chain / P55103* / inhibin beta C subunit*  / complex






 

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